These days, an increasing number of people seeking IVF treatments are experiencing failure in IVF treatment. If a woman experiences more than three failed in vitro fertilization (IVF) attempts with good quality embryos, it is referred to as recurrent implantation failure (RIF).

However, they should try and keep up their hope and faith and seek suitable treatment to prevent it from happening repeatedly. They need to approach an IVF specialist who has treated similar cases and can help them realize their dream of bearing children.

Dr Nisarg Patel, Laparoscopic Surgeon and IVF doctor of a leading IVF centre in Ahmedabad, states that ‘Cases of recurrent IVF failure need individualized treatment after a thorough investigation of causes of failure of past IVF cycles. Along with uterine health, sperm analysis, pre-implantation genetic screening and endometrial receptivity are conducted and their results evaluated.’ Dr Nisarg Patel, a leading IVF doctor in Ahmedabad, is an expert in treating cases of recurring IVF failure. He has performed more than 8000 IVF cycles with a success rate of 60%.

The other factors leading to IVF failure could be male or embryo or uterine factors or certain IVF protocols. Therefore, such cases need in-depth investigations across several variables such as immunological factors, uterine pathologies and conditions that could be causing IVF failure repeatedly.

Since we refer to embryo implantation failure, the couple should approach an IVF specialist who has successfully treated similar cases. The IVF specialist recommends the most suitable treatment after going through the results of the advanced diagnosis. If advanced maternal age is the reason for recurring IVF failure, it is advisable to use donor eggs used in IVF. In addition, it is advisable to remove the polyps or fibroids if detected in the uterus before the implantation procedure. Also, embryo transfer is best done through a catheter and ultrasonic images.

In another recent development, IVF specialists use EmbryoGlue as a medium to increase the chance of successful implantation. They place the embryo in the EmbryoGlue, a high concentration of hyaluronan and recombinant human albumin, both of which promote implantation. In addition, the EmbryoGlue offers an environment similar to that of within the womb with nutrients and energy which also nourish the embryo.

Elaborating on the reasons for recurring IVF failure, Dr Nisarg Patel states that other than age and lifestyle disorders, cytokine levels, specific autoantibodies, and infectious organisms in the uterus need to be checked as they lead to chronic endometritis. In addition, it is advisable to perform a further screening of the uterus for myomas, polyps, and congenital anatomical anomalies.

It is essential to get a sperm analysis done, while pre-implantation genetic screening and endometrial receptivity are essential for the birth of a normal and healthy baby. The treating IVF specialist will suggest a customized IVF plan and proceed with the IVF cycle depending on these reports.

About Dr Nisarg Patel and Nisha IVF, Ahmedabad

Nisha IVF centre,Ahmedabad is established by Dr Nisarg Patel, Dr HimaliManiar and Dr H. B. Patel, leading gynecologists, to serve the residents of Ahmedabad, Gujarat and nearby states. Nisha IVF Centre and the team of doctors have successfully treated nearly 450+ couples. They are extremely warm, kind and friendly in approach and patiently resolve all IVF-related queries.

Dr Nisarg Patel is the Director, Consultant Gynecologist-Obstetrician, Laparoscopic Surgeon and IVF doctor with more than ten years of experience in the treatment of IVF, male infertility treatment, female infertility treatment, treatment for repeated IVF failures, frozen embryo transfer, and recurring IVF failure.

He has acquired fellowships in Infertility & IVF and Obstetrics and Gynecology Ultrasound from IKDRC, Ahmedabad. In addition, he has helped establish IVF clinics and management in Mumbai, Rajkot, Ajmer, Botad, Surendranagar and Nepal.

Nisha IVF is located at 201, 2nd Floor, Bhavya Shopping Complex, opp. Govt Tubewell, Bopal, Ahmedabad, Gujarat 380058,India and for further enquiries please email at nishahospital.ivf@gmail.com or call on 9081233800, 2717233800.